基本信息
产品名称 | 微囊藻毒素Microcystin-LR |
---|---|
英文名称 | microcystin lr |
别名 | Microcystin-LR;生物毒素, 蓝藻毒素, 藻华毒素,快速死亡因子 |
英文别名 | Microcystin-LR;Biotoxin;Algae bloom toxin;Cyanobacterial toxin |
规格或纯度 | Concentration in Methanol/Water(1/1) |
运输条件 | 超低温冰袋运输 |
一般描述
产品介绍:
Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.
产品用途:
Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).
Product introduction:
Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.
Application:
Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).
安全信息
标识符号 | GHS06, GHS08, GHS02 |
---|---|
信号词 | Danger |
警示性声明 | P280,P311,P210,P302+P352,P312,P301+P330+P331,P304+P340 |
危害声明 | H225,H301+H331,H301+H311 |
个人防护设备 | Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US) |
RIDADR | UN1230 – class 3 – PG 2 – Methanol, solution |
WGK | WGK 2 |
相关属性
CAS编号 | 101043-37-2 |
---|---|
敏感性 | 对热敏感 |
储存温度 | -20°C储存 |
MDL号 | MFCD01774058 |
分子量 | 995.1717 |
分子式 | C49H74N10O12 |
EC号 | 200-659-6 |
品牌 | 金畔生物 |
PubChem CID | 445434 |
INCHI | 1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28- |
InChi Key | ZYZCGGRZINLQBL-GWRQVWKTSA-N |