微囊藻毒素Microcystin-LR


基本信息

产品名称 微囊藻毒素Microcystin-LR
英文名称 microcystin lr
别名 Microcystin-LR;生物毒素, 蓝藻毒素, 藻华毒素,快速死亡因子
英文别名 Microcystin-LR;Biotoxin;Algae bloom toxin;Cyanobacterial toxin
规格或纯度 Concentration in Methanol/Water(1/1)
运输条件 超低温冰袋运输

一般描述

产品介绍:

Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.

产品用途:

Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).

Product introduction:

Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.

Application:

Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).

安全信息

标识符号 微囊藻毒素Microcystin-LR GHS06, 微囊藻毒素Microcystin-LR GHS08, 微囊藻毒素Microcystin-LR GHS02
信号词 Danger
警示性声明 P280,P311,P210,P302+P352,P312,P301+P330+P331,P304+P340
危害声明 H225,H301+H331,H301+H311
个人防护设备 Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
RIDADR UN1230 – class 3 – PG 2 – Methanol, solution
WGK WGK 2

相关属性

CAS编号 101043-37-2
敏感性 对热敏感
储存温度 -20°C储存
MDL号 MFCD01774058
分子量 995.1717
分子式 C49H74N10O12
EC号 200-659-6
品牌 金畔生物
PubChem CID 445434
INCHI 1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28-
InChi Key ZYZCGGRZINLQBL-GWRQVWKTSA-N

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