盐酸Dojindo,6-氨基-1-六硫醇/100/A425

氨基烷硫醇用于修饰金表面以在表面上引入氨基。 Dojindo 新开发的 16-Amino-1-hexadecanethiol 具有 16 个碳链,是市场上最长的烷硫醇。由于烷烃基团之间的范德华力较大,预计在氨基烷硫醇化合物中,16-氨基-1-十六烷硫醇将在金表面上形成最稳定的SAM。五种不同的氨基烷硫醇,包括氨基-EG6-十一烷硫醇、盐酸盐,可用于金表面改性。氨基-EG6-十一硫醇用于亲水表面制备。氨基通常使用胺反应性材料(例如蛋白质或生物材料)进行修饰,以使金表面功能化。一些研究人员已经报道了短烷基链氨基烷硫醇的 SAM,并且关于长烷基链化合物的报道越来越多。 Takahara 等人在金电极上形成了单层 11-氨基-1-十一硫醇,并使用伏安法研究了末端基团对二茂铁衍生物氧化还原反应的影响。他们还报道了氨基烷硫醇的烷基链长度与连接到末端氨基的 2,3-二氯-1,4-萘醌的氧化还原行为之间的关系。 Tanahashi 和同事用几种功能化烷硫醇的 SAM 修饰了金表面。他们使用 X 射线光电子能谱 (XPS) 测量和石英晶体微天平 (QCM) 方法报告了其末端官能团对模拟体液中磷灰石形成的影响。

How to prepare the SPR-Chip:

1. J. M. Brockman, A. G. Frutos and R. M. Corn, A Multistep Chemical Modification Procedure To Create DNA Arrays on Gold Surface for the Study of Protein-DNA Interactions with Surface Plasmon Resonance Imaging, J. Am. Chem. Soc., 1999, 121, 8044.2. Y. Yoshimi, T. Matsuda, Y. Itoh, F. Ogata and T. Katsube, Surface Modifications of Functional Electrodes of a Light Addressable Potentiometric Sensor (LAPS): Non-Dependency of pH Sensitivity on the Surface Functional Group, Mater. Sci. Eng. C, 1997, 5, 131.3. M. Tanahashi and T. Matsuda, Surface Functional Group Dependence on Apatite Formation on Self-assembled Monolayers in a Simulated Body Fluid, J. Biomed. Mater. Res., 1997, 34, 305.4. J. Tien, A. Terfort and G. M. Whitesides, Microfaburication through Electrostatic Self-Assembly, Langmuir, 1997, 13, 5349.5. F. Mukae, H. Takemura and K. Takehara, Electrochemical Behavior of the Naphtoquinone Anchored onto a Gold Electrode through the Self-Assembled monolayers of Aminoalkanethiol, Bull. Chem. Soc. Jpn., 1996, 69, 2461.6. S. Rubin, G. Bar, R. W. Cutts, J. T. Chow, J. P. Ferraris, and T. A. Zawodzinski, Electrical Communication Between Glucose Oxidase and Different Ferrocenylalkanethiol Chain Lengths, Mater. Res. Soc. Symp. Proc., 1996, 413, 377.7. K. Takehara and H. Takemura, Electrochemical Behaviors of Ferrocene Derivatives at an Electrode Modified with Terminally Substituted Alkanethiol Monolayer Assemblies, Bull. Chem. Soc. Jpn., 1995, 68, 1289.8. K. Takehara, H. Takemura and Y. Ide, Electrochemical Studies of the Terminally Substituted Alkanethiol Monolayers Formed on a Gold Electrode; Effect of the Terminal Group on the Redox Responses of Fe(CN)63-,Ru(NH3)63+ and Ferrocenedimethanol, Electrochim. Acta, 1994, 39, 817.

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