lonza,原代细胞和干细胞,lonza 00225974,hVIC – 人瓣膜间质细胞

Product Overview

The aortic valve is a valve in the human heart between the left ventricle and the aorta. The valve undergoes exceptional forces due to blood flow during each cardiac cycle. The two primary cell types in the aortic valve are the aortic valve endothelial cells (HAoVEC) which provide the barrier function as the valve opens and closes and the valvular interstitial Cells (hVIC) which provide the structural integrity of the valve.

Lonza’s Human Valvular Interstitial Cells (hVIC) are provided as a made to order product by Lonza’s CellBio Services custom cell isolation team.

Cryopreserved Human Valvular Interstitial Cells (hVIC) are tested for expression levels of Factor VIII and Alpha Smooth Muscle Actin, viability, plating efficiency, and doubling time. All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

This product can be provided on its own or as a matched set with Human Aortic Valve Endothelial Cells (HAoVEC; part number 00225975). This product is also customizable to allow for larger batch sizes, additional testing specifications, or specific donor requirements.

主动脉瓣是人心脏中左心室和主动脉之间的瓣膜。由于每个心动周期中的血流，瓣膜会受到异常的作用力。主动脉瓣中的两种主要细胞类型是在瓣膜打开和关闭时提供屏障功能的主动脉瓣内皮细胞 (HAoVEC) 和提供瓣膜结构完整性的瓣膜间质细胞 (hVIC)。

Lonza 的人瓣膜间质细胞 (hVIC) 作为定制产品由 Lonza 的 CellBio Services 定制细胞分离团队提供。

检测冷冻保存的人瓣膜间质细胞 (hVIC) 的因子 VIII 和 Alpha 平滑肌肌动蛋白的表达水平、活力、铺板效率和倍增时间。所有细胞的支原体、细菌、酵母和真菌均呈阴性。并非所有供体和/或细胞批次都检测到 HIV-1、乙型肝炎和丙型肝炎。为购买的每个细胞批次提供分析证书。

该产品可以单独提供，也可以与人主动脉瓣内皮细胞（HAoVEC；部件号 00225975）配套提供。该产品还可以定制，以允许更大的批量、额外的测试规范或特定的捐助者要求。

Safety Data Sheets (SDS)

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.