标签：microcystin

微囊藻毒素Microcystin-RR


基本信息

产品名称 微囊藻毒素Microcystin-RR
英文名称 Microcystin-RR
规格或纯度 10ug/ml

一般描述

产品介绍：

Microcystin-RR is a microcystin generally produced by cyanobacteria.

产品用途：

Microcystin-RR may be used as an analytical reference standard for the quantification of the analyte in water samples using high-performance liquid chromatography with diode array detection (HPLC-DAD).

Product introduction：

Microcystin-RR is a microcystin generally produced by cyanobacteria.

Application：

Microcystin-RR may be used as an analytical reference standard for the quantification of the analyte in water samples using high-performance liquid chromatography with diode array detection (HPLC-DAD).

相关属性

CAS编号 111755-37-4
敏感性 对光线敏感
储存温度 storage temp. -20°C
分子量 1038.218
分子式 C49H75N13O12
品牌 金畔生物
PubChem CID 6438357

微囊藻毒素Microcystin-LA


基本信息

产品名称 微囊藻毒素Microcystin-LA
英文名称 Microcystin-LA
别名 Biotoxin；Algae bloom toxin；Cyanobacterial toxin
英文别名 Biotoxin；Algae bloom toxin；Cyanobacterial toxin
应用 Microcystin LA 是一种天然毒素，Microcystin LA 通过抑制丝氨酸-苏氨酸蛋白磷酸酶 PP1 (IC50=0.3 nM) 和 PP2A (IC50=0.3 nM) 来发挥其细胞毒性作用。
规格或纯度 10ug/ml in methanol
运输条件 干冰运输
生化机理 微囊藻毒素 LA 抑制蛋白磷酸酶类型 A 型和蛋白磷酸酶 3 类型的能力强于蛋白磷酸酶 1 类型（效价顺序 PP2A > PP3 > PP1）。诱导中性粒细胞活化趋化因子和胞外活性氧，可能的机制是其肝毒性作用。

一般描述

产品介绍：

微囊藻毒素是一种单环小分子多肽，由 7 个氨基酸通过肽键连接而成。是一种具有肝毒性和促癌属性的青毒素。鱼腥藻属、 丝囊藻属、 微胞藻属 和 浮丝藻属等几个藻属产生微囊藻毒素。微囊藻毒素有四种同源物，即-LR、-LA、-YR 和-RR。

产品用途：

Microcystin LA inhibit PP1 and PP2A quite potently and specifically relative to other known phosphatases, such as PP2B (calcineurin), PP2C, and the tyrosine phosphatases

Product introduction:

Microcystin is a small, monocyclic peptide, composed of seven amino acids connected via peptide bonds. It is a cyanotoxin with hepatotoxic and tumor promoting properties. Several algal genera like Anabaena, Aphanizomenon, Microcystis and Planktothrix produce microcystin.[2] Microcystin has four congeners namely, -LR, -LA, -YR and -RR.

Application：

Microcystin LA inhibit PP1 and PP2A quite potently and specifically relative to other known phosphatases, such as PP2B (calcineurin), PP2C, and the tyrosine phosphatases

安全信息

标识符号 微囊藻毒素Microcystin-LA GHS06
信号词 Danger
警示性声明 P305+P351+P338,P280,P301+P310,P310,P302+P352,P304+P340,P330,P262
危害声明 H315,H319,H335,H317,H300+H310+H330
个人防护设备 Eyeshields, Faceshields, Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RIDADR UN 2811PIH 6.1 / PGI
WGK WGK 3

相关属性

CAS编号 96180-79-9
溶解性 methanol: 2 mg/mL
储存温度 −20°C
分子量 910.06
分子式 C46H67N7O12
品牌 金畔生物

微囊藻毒素Microcystin-WR


基本信息

产品名称 微囊藻毒素Microcystin-WR
英文名称 Microcystin-WR
别名 生物毒素, 蓝藻毒素, 藻华毒素
英文别名 Biotoxin；Algae bloom toxin；Cyanobacterial toxin
规格或纯度 10ug/ml in methanol
运输条件 干冰运输

一般描述

产品介绍：

Microcystins (MCs) are hepatotoxic cyclic heptapeptides, produced by various cyanobacterial species. MC’s cause adverse effects on freshwater systems with algae blooms.

Microcystin WR contains tryptophane (W) in position 2 and arginine (R) in position 4.Microcystins are potent inhibitors of protein phosphatase types 1 and 2A (IC50 value of MC-WR for inhibiting PP2A = 0.18 nM). No effects on protein kinases are known. MCs are known to be hepatic tumor promoters in experimental animal models.

Product introduction：

Microcystins (MCs) are hepatotoxic cyclic heptapeptides, produced by various cyanobacterial species. MC’s cause adverse effects on freshwater systems with algae blooms.

Microcystin WR contains tryptophane (W) in position 2 and arginine (R) in position 4.Microcystins are potent inhibitors of protein phosphatase types 1 and 2A (IC50 value of MC-WR for inhibiting PP2A = 0.18 nM). No effects on protein kinases are known. MCs are known to be hepatic tumor promoters in experimental animal models.

相关属性

CAS编号 138234-58-9
敏感性 Soluble in methanol or DMSO
溶解性 Soluble in methanol or DMSO
储存温度 −20°C
分子量 1068.22
分子式 C54H73N11O12
品牌 金畔生物

微囊藻毒素Microcystin-LF


基本信息

产品名称 微囊藻毒素Microcystin-LF
英文名称 Microcystin-LF
别名 藻华毒素；Biotoxin；Algae bloom toxin；Cyanobacterial toxin
英文别名 Biotoxin；Algae bloom toxin；Cyanobacterial toxin
应用 Microcystin-LF may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).
规格或纯度 10ug/ml in methanol
运输条件 干冰运输

一般描述

产品介绍：

Microcystin-LF is a toxic analog of microcystin produced by cyanobacteria in freshwater systems.
产品用途：

Microcystin-LF may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).

Product introduction：

Microcystin-LF is a toxic analog of microcystin produced by cyanobacteria in freshwater systems.
Application：

Microcystin-LF may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).

安全信息

标识符号 微囊藻毒素Microcystin-LF GHS06, 微囊藻毒素Microcystin-LF GHS08, 微囊藻毒素Microcystin-LF GHS02
信号词 Danger
警示性声明 P280,P311,P210,P302+P352,P312,P304,P340,P301+P330+P331
危害声明 H331,H225,H370,H301+H311
个人防护设备 Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
RIDADR UN1230 – class 3 – PG 2 – Methanol, solution

相关属性

CAS编号 154037-70-4
储存温度 −20°C
MDL号 MFCD16661164
分子量 986.16
分子式
EC号 200-659-6
品牌 金畔生物

微囊藻毒素Microcystin-YR


基本信息

产品名称 微囊藻毒素Microcystin-YR
英文名称 Microcystin-YR
别名 生物毒素; 蓝藻毒素;藻华标准品;藻华毒素
英文别名 Algae bloom standard, Algae bloom toxin, Biotoxin, Cyanobacterial toxin
规格或纯度 10ug/ml in methanol
运输条件 超低温冰袋运输

一般描述

产品介绍：

Microcystin-YR is a microcystin that is generally produced by cyanobacteria.

产品用途：

Microcystin-YR may be used as an analytical reference standard for the quantification of the analyte in water samples using high-performance liquid chromatography with diode array detection (HPLC-DAD).

Product introduction：

Microcystin-YR is a microcystin that is generally produced by cyanobacteria.

Application：

Microcystin-YR may be used as an analytical reference standard for the quantification of the analyte in water samples using high-performance liquid chromatography with diode array detection (HPLC-DAD).

安全信息

标识符号 微囊藻毒素Microcystin-YR GHS06, 微囊藻毒素Microcystin-YR GHS08, 微囊藻毒素Microcystin-YR GHS02
信号词 Danger
警示性声明 P301+P310,P370+P378,P403+P235,P303+P361+P353,P304+P340,P403+P233,P308+P311
危害声明 H331,H225,H370,H301+H311

相关属性

CAS编号 101064-48-6(methanol)
储存温度 -20°C储存
分子式
品牌 金畔生物

微囊藻毒素Microcystin-LY


基本信息

产品名称 微囊藻毒素Microcystin-LY
英文名称 Microcystin-LY
别名 生物毒素, 蓝藻毒素, 藻华毒素
英文别名 Biotoxin；Algae bloom toxin；Cyanobacterial toxin
规格或纯度 10ug/ml in methanol
运输条件 干冰运输

一般描述

产品介绍：

Microcystin-LY is generally produced by cyanobacteria in freshwater systems and is found as a toxic analog of microcystin.
产品用途：

Microcystin-LY may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).

Product introduction：

Microcystin-LY is generally produced by cyanobacteria in freshwater systems and is found as a toxic analog of microcystin.
Application：

Microcystin-LY may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).

安全信息

标识符号 微囊藻毒素Microcystin-LY GHS06, 微囊藻毒素Microcystin-LY GHS08, 微囊藻毒素Microcystin-LY GHS02
信号词 Danger
警示性声明 P280,P301+P310,P311,P210,P302+P352,P312,P304,P340,P330
危害声明 H301,H311,H331,H225,H370
个人防护设备 Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
RIDADR UN1230 – class 3 – PG 2 – Methanol, solution
WGK WGK 2
闪点（摄氏） 746.2±34.3 °C

相关属性

CAS编号 123304-10-9
沸点 1310.2±65.0 °C at 760 mmHg
储存温度 −20°C
MDL号 MFCD10567358
分子量 1002.1592
分子式 C52H71N7O13
品牌 金畔生物
PubChem CID 71312414
IIUPAC Name InChI=1S/C52H71N7O13/c1-28(2)24-40-50(67)58-44(52(70)71)32(6)46(63)56-41(26-36-17-19-37(60)20-18-36)49(66)54-38(21-16-29(3)25-30(4)42(72-10)27-35-14-12-11-13-15-35)31(5)45(62)55-39(51(68)69)22-23-43(61)59(9)34(8)48(65)53-33(7)47(64)57-40/h11-21,25,28,30-3
InChi Key SIGQAYSWORHPPH-KXMJXUBPSA-N

微囊藻毒素Microcystin-LR


基本信息

产品名称 微囊藻毒素Microcystin-LR
英文名称 microcystin lr
别名 Microcystin-LR;生物毒素, 蓝藻毒素, 藻华毒素，快速死亡因子
英文别名 Microcystin-LR;Biotoxin；Algae bloom toxin；Cyanobacterial toxin
规格或纯度 Concentration in Methanol/Water(1/1)
运输条件 超低温冰袋运输

一般描述

产品介绍：

Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.

产品用途：

Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).

Product introduction：

Microcystins are toxic molecules produced by cyanobacterial blooms due to water eutrophication. Microcystin-LR proves to be a potent inhibitor of type 1 (IC50=1.7 nM) and type 2A (IC50= 0.04 nM) protein phosphatases. Microcystin-LR inhibits the activity of both type 1 and type 2A phosphatases >10-fold more potently than okadaic acid under the same conditions. Type 2A protein phosphatases in dilute mammalian cell extracts are found to be completely inhibited by 0.5 nM microcystin-LR while type 1 protein phosphatases are only slightly affected at this concentration.

Application：

Microcystin-LR may be used as an analytical reference standard for the determination of the analyte in surface water samples using high-performance liquid chromatography coupled to tandem mass spectrometry with electrospray ionization source (HPLC-ESI-MS/MS).

安全信息

标识符号 微囊藻毒素Microcystin-LR GHS06, 微囊藻毒素Microcystin-LR GHS08, 微囊藻毒素Microcystin-LR GHS02
信号词 Danger
警示性声明 P280,P311,P210,P302+P352,P312,P301+P330+P331,P304+P340
危害声明 H225,H301+H331,H301+H311
个人防护设备 Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
RIDADR UN1230 – class 3 – PG 2 – Methanol, solution
WGK WGK 2

相关属性

CAS编号 101043-37-2
敏感性 对热敏感
储存温度 -20°C储存
MDL号 MFCD01774058
分子量 995.1717
分子式 C49H74N10O12
EC号 200-659-6
品牌 金畔生物
PubChem CID 445434
INCHI 1S/C49H74N10O12/c1-26(2)23-37-46(66)58-40(48(69)70)30(6)42(62)55-35(17-14-22-52-49(50)51)45(65)54-34(19-18-27(3)24-28(4)38(71-10)25-33-15-12-11-13-16-33)29(5)41(61)56-36(47(67)68)20-21-39(60)59(9)32(8)44(64)53-31(7)43(63)57-37/h11-13,15-16,18-19,24,26,28-
InChi Key ZYZCGGRZINLQBL-GWRQVWKTSA-N

微囊藻毒素Microcystin-LW


基本信息

产品名称 微囊藻毒素Microcystin-LW
英文名称 Microcystin-LW
别名 生物毒素, 蓝藻毒素, 藻华毒素；15-(1H-indol-3-ylmethyl)-18-[(1z,3e)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,19-tetramethyl-2-methylidene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclope
英文别名 Biotoxin；Algae bloom toxin；Cyanobacterial toxin；15-(1H-indol-3-ylmethyl)-18-[(1z,3e)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dienyl]-1,5,12,19-tetramethyl-2-methylidene-8-(2-methylpropyl)-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptazacyclope
应用 Microcystin-LW may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).
规格或纯度 10ug/ml in methanol
运输条件 干冰运输

一般描述

产品介绍：

Microcystin-LW is a toxic analog of microcystin produced by cyanobacteria in freshwater systems.
产品用途：

Microcystin-LW may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).

Product introduction：

Microcystin-LW is a toxic analog of microcystin produced by cyanobacteria in freshwater systems.
Application：

Microcystin-LW may be used as an analytical reference standard for the determination of the analyte in raw and treated waters using high-performance liquid chromatography with photo-diode array detection (HPLC-PDA).

安全信息

标识符号 微囊藻毒素Microcystin-LW GHS06, 微囊藻毒素Microcystin-LW GHS08, 微囊藻毒素Microcystin-LW GHS02
信号词 Danger
警示性声明 P280,P301+P310,P210,P310,P302+P352,P312,P304+P340,P330
危害声明 H301,H311,H225,H334,H330,H370
个人防护设备 Eyeshields, Faceshields, Gloves, multi-purpose combination respirator cartridge (US)
RIDADR UN1230 – class 3 – PG 2 – Methanol, solution
WGK WGK 2

相关属性

CAS编号 157622-02-1
储存温度 −20°C
MDL号 MFCD16661165
分子量 1025.2
分子式 C54H72N8O12
品牌 金畔生物
PubChem CID 16760564
INCHI 1S/C54H72N8O12/c1-29(2)24-42-52(69)61-46(54(72)73)33(6)48(65)59-43(27-37-28-55-40-19-15-14-18-38(37)40)51(68)57-39(21-20-30(3)25-31(4)44(74-10)26-36-16-12-11-13-17-36)32(5)47(64)58-41(53(70)71)22-23-45(63)62(9)35(8)50(67)56-34(7)49(66)60-42/h11-21,25,28-2
InChi Key CJIASZBWXIFQMU-LNXRSHCCSA-N