lonza R-CB-503,原代细胞和干细胞,大鼠小脑颗粒神经元

Catalog #: R-CB-503

Cryopreserved ampule of Rat Cerebellar Granular Neurons containing ≥ 4 million cells

Product Overview

CloneticsTM 大鼠小脑颗粒细胞是从成年 Sprague Dawley 大鼠出生后第 8 天的小脑皮质中分离出来的。小脑颗粒细胞利用谷氨酸作为其神经递质,因此是小脑皮质内唯一的兴奋性神经元。

所有其他神经元细胞类型都使用 GABA 作为神经递质。 颗粒细胞出现在小脑皮层神经元发育的后期,是哺乳动物大脑中最丰富的单一神经元类型。 根据 GABA 免疫反应性评估,这些是高度同质的颗粒细胞群,含有少于 5% 的 GABA 能神经元。

推荐媒体:PNGMTM-A BulletKitTM (CC-4512)

Benefits

  • Ready-To-Use
  • >95% pure granular cells, with glia
  • No tissue dissection or animal handling required
  • Increased data reproducibility
  • Characteristic morphology and staining tests confirm tissue origin and cell type
  • Negative for mycoplasma, bacteria, yeast and fungi
  • Certificate of Analysis (CoA) is available for every batch

Applications

  • Electrophysiology
  • Neurotransmitter release
  • Ion channels
  • Glutamate receptor biology
  • Neuronal apoptosis and toxicity
  • Nitric Oxide and cGMP pathway
  • Neurite outgrowth

Content & Storage

Content

≥ 4,000,000 cryopreserved cells per ampule

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