标签：BrightSite™ IRDye® in vivo Imaging Agents

Every LI-COR BrightSite IRDye in vivo imaging agent has been carefully validated with cultured cell assays, microscopy, in vivo imaging of animal models, and histology to ensure high affinity and specificity.

BrightSite IRDye Small Animal Imaging Agents are:

• Ready-to-use probes that are simple to administer, allowing you to begin animal studies immediately
• Sensitive, offering the high signal-to-noise advantages of near-infrared fluorescence which are especially important for small or deep targets
• Cited in several hundred peer-reviewed publications so you can use them with confidence
• Imaged with any small animal imaging equipment with appropriate 680 nm or 800 nm filter sets
• Compatible with most small animal imaging systems, including instruments from LI-COR Biosciences (Pearl^® and Odyssey^®), PerkinElmer (Xenogen, Caliper, CRi, and VisEn), and Bruker (Carestream and Kodak)
• 易于管理的即用型探针，可让您立即开始动物研究
  灵敏，提供近红外荧光的高信噪比优势，这对于小目标或深目标尤其重要
  在数百篇同行评审的出版物中被引用，因此您可以放心使用它们
  使用任何带有适当 680 nm 或 800 nm 滤光片组的小动物成像设备进行成像
  与大多数小动物成像系统兼容，包括来自 LI-COR Biosciences（Pearl® 和 Odyssey®）、PerkinElmer（Xenogen、Caliper、CRi 和 VisEn）和 Bruker（Carestream 和 Kodak）的仪器

IRDye 800CW absorption/emission near 800 nm matches near-infrared absorption minima for bodily fluids and tissues, resulting in excellent tissue penetration, making it ideal for in vivo imaging.

Detect Apoptotic and Necrotic Cells, Bacteria and Other Anionic Membranes

LI-COR also offers the PSVue^® 794 Reagent Kit which can be used to detect apoptotic and necrotic cells, bacteria and other anionic membranes.

LI-COR 还提供 PSVue® 794 试剂盒，可用于检测凋亡和坏死细胞、细菌和其他阴离子膜。

Fluorescently Label Cells or Tissues for in vivo or in vitro Studies

CellVue^® fluorescent imaging kits use proprietary labeling technology to stably incorporate fluorescent dyes containing long aliphatic hydrocarbon tails into lipid membranes.¹ They are useful for researchers working in all aspects of science and technology where fluorescently-labeled cells and/or tissues are required. CellVue dyes also provide researchers with valuable tools for many in vivo and in vitro cell studies using fluorescent membrane labels.

CellVue® 荧光成像试剂盒使用专有的标记技术，将含有长脂肪烃尾的荧光染料稳定地掺入脂质膜中。1 它们适用于在需要荧光标记的细胞和/或组织的科学和技术的各个方面工作的研究人员。 CellVue 染料还为研究人员提供了许多使用荧光膜标记进行体内和体外细胞研究的宝贵工具。

CellVue dyes consist of long aliphatic hydrocarbon tails linked to a polar fluorescent chromophore.

• These extremely lipophilic fluorescent dyes rapidly and stably integrate into the phospholipid membrane of cells or other membrane-containing bioparticles by non-covalent interactions
• The dyes are stably maintained within the lipid bilayer through strong hydrophobic interactions and do not transfer into the unstained membranes of adjacent cells, which permits a labeled cell to be tracked for extended periods of time
• The rapid incorporation of the dye allows for immediate analysis of cell functions without a waiting period

Selecting the Right Optical Imaging Agent

Application	IRDye EGF	IRDye RGD	IRDye 2-DG	IRDye PEG	IRDye BoneTag	CellVue	PSVue
Tumor Imaging
Metabolic Imaging
Inflammation/Arthritis
Vasculature (Contrast)
Lymphatic Imaging
Lymph Node Imaging
Structural Imaging
Cell Trafficking
Apoptosis

References

1. Horan, P. K., and Slezak, S. E. (1989) Nature, 340. 167-168.