Specificity of Anti 8-Nitroguanosine monoclonal antibody
Tissue Staining with Anti-Nitroguanosine AntibodyA) Tissue section (8 days postinfection, influenza) stained with Anti-Nitroguanosine Antibody.B) The same section viewed using a confocal laser scanning microscope (Fluoroview FV300, Olympus, Nagano, Japan). Strong fluorescence, due to emission of Vector red, is evident in the cytosol.
1. T. Akaike, et al., 8-nitroguanosine formation in viral pneumonia and its implication for pathogenesis, PNAS. 2003;100:685-690.2. J. Yoshitake, et al., Nitric oxide as an endogenous mutagen for Sendai virus without antiviral activity. J Virol. 2004;78:8709-8719.3. T. Sawa, et al., Protein S-guanylation by the biological signal 8-nitroguanosine 3 E5 Ecyclic monophosphate. Nat Chem Biol. 2007;3:727-735.4. M. H. Zaki, et al., Cytoprotective function of heme oxygenase 1 induced by a nitrated cyclic nucleotide formed during murine salmonellosis. J Immunol. 2009;182:3746-3756.5. Y. Terasaki, et al., Guanine nitration in idiopathic pulmonary fibrosis and its implication for carcinogenesis. Am J Respir Crit Care Med. 2006;174:665-673.6. T. Sawa, et al., Analysis of urinary 8-nitroguanine, a marker of nitrative nucleic acid damage, by high-performance liquid chromatography-electrochemical detection coupled with immunoaffinity purification: association with cigarette smoking. Free Radic Biol Med. 2006;40:711-720.