2022 3月 25 | BETHYL抗体金畔生物官网

lonza,原代细胞和干细胞,Human Cryo Kupffer Cells, 0.2 Million

Catalog #: HLKC-200K

Naïve Kupffer cells derived from human liver tissue. 0.2 million cells per vial

Overview

Product Overview

Kupffer cells are the resident macrophages in the liver and are part of the first line of defense against bacteria and toxins in the gut. Kupffer cells exhibit typical macrophage morphology and can be activated to produce inflammatory cytokines, growth factors and reactive oxygen species.

In vivo, prolonged activation of Kupffer cells are associated with many diseases of the liver including Non-alcoholic Fatty Liver Disease (NAFLD), Non Alcoholic Steato Hepatitis (NASH), and liver damage associated with certain bioactivated chemicals. Human Cryopreserved Kupffer cells are isolated and enriched from dissociated human liver tissue and then cryopreserved as passage 0. Characterization of isolated Kupffer cells includes assessing morphology in plated format and evaluating functional responses to LPS stimulation.

Benefits

LPS Inducible
High activation potential
Naïve primary cells – never has contacted plastic dish

Applications

ADMETox
Disease research

Content & Storage

Content

Cryopreserved Cells, > 200K viable cells

Instructions, SDS, CoA

Safety Data Sheets (SDS)

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SDS – Dutch

SDS – German

SDS – Italian

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SDS – French

SDS – English

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

FAQ & Citations

lonza,原代细胞和干细胞,Cord Blood CD34+ ≥2 million cells

Catalog #: 2C-101X

Cryopreserved ampule of Human Cord Blood CD34+ stem/progenitors containing ≥2 million cells

This product is also available with HLA information if your research requires it:
≥1 million cells
≥ 2 million cells

Overview

Product Overview

Lonza cord blood CD34+ cells (2C-101X) contain hematopoietic stem and progenitor cells, are isolated from cord blood mononuclear cells (MNCs) via positive immunomagnetic separation. They are ideal for studies relating to transplantation and stem cells and humanized mouse model development. The number of cells typically obtained from cord blood can be limiting and pose a challenge. Cord blood derived CD34+ (2C-101X) consists of ≥2 million cells hematopoietic stem cells from the same donor. Cells are ethically sourced and are isolated using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols. Large inventory supports stable supply from a single vendor.

Guarantee

Lonza guarantees the performance of Cells only if appropriate Lonza recommended Media and Reagents are used exclusively and the recommended storage and use protocols are followed. Any modifications made to the recommended cell systems including the use of alternative media, reagents or protocols, will void cell and media performance guarantees. If you need assistance in selecting the appropriate media, reagents, or protocol, please contact Lonza Scientific Support.

Benefits

More cells: Increase productivity with larger number of cells available from a single donor

High Purity Viability: Guaranteed to have a purity of ≥90% as indicated by CD34+ expression

High viability: They are guaranteed to contain ≥2 million viable cells per ampoule

Certificate of Analysis is provided for each cell lot purchased. HIV, HBV, HCV not detected

Supporting media: Use X-VIVO^{^®} 20 Medium for the expansion and differentiation.

Choices in CD34+ cell types: (2C-101 H) and 2C-101 HX are available with HLA information. CD34+ cells derived from bone marrow (2M-101) and from adult mobilized blood (4Y-101D) are also available.

Applications

Humanized mice models creation
CAR-T therapy process development
Regenerative medicine
Autoimmune disease
Transplantations studies
Immunology
Cancer research

Instructions, SDS, CoA

Instructions

1 of

Safety Data Sheets (SDS)

View SDS

SDS – Dutch

SDS – German

SDS – Italian

SDS – Spanish

SDS – French

SDS – English

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

Brochures, White Papers etc.

1 of

Data

1 of

FAQ & Citations

lonza,lonza 2C-101HX,脐带血 CD34+ ≥2 million cells w/ HLA

Catalog #: 2C-101HX

Cryopreserved ampule of Human Cord Blood CD34+ stem/progenitors containing ≥2 million cells with HLA information

人脐带血 CD34+ 干/祖细胞的冷冻保存安瓿，含有 ≥ 200 万个具有 HLA 信息的细胞

This product is also available without HLA information if your research does not require it:
≥1 million cells
≥ 2 million cells

Overview

Product Overview

Lonza cord blood CD34+ HLA cells (2C-101HX) contain ≥2 Million hematopoietic stem and progenitor cells, and are ideal for studies relating to transplantation and stem cells and humanized mouse model creation. Cord blood derived CD34+ HLA cells (2C-101HX) is available with HLA information. This eliminates the need to use cells for obtaining HLA genotype and increases the number of cells that can be used within your experiment. It also can be used to select lots more appropriate for your needs. Large lot sizes of ≥2 Million cells increase productivity of transplantation experiments. The combined value of large lot and HLA information provides considerable time and cost savings. Cord blood CD34+ HLA cells are ethically sourced and are isolated using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols.

Lonza 脐血 CD34+ HLA 细胞 (2C-101HX) 含有 ≥ 200 万个造血干细胞和祖细胞，是与移植和干细胞相关的研究以及人源化小鼠模型创建的理想选择。脐带血来源的 CD34+ HLA 细胞 (2C-101HX) 可提供 HLA 信息。这消除了使用细胞获取 HLA 基因型的需要，并增加了可在您的实验中使用的细胞数量。它也可用于选择更适合您需要的批次。 ≥200 万个细胞的大批量可提高移植实验的效率。大批量和 HLA 信息的综合价值可节省大量时间和成本。脐带血 CD34+ HLA 细胞来源合乎道德，并使用机构审查委员会 (IRB) 或其他监管机构批准的同意书和协议进行分离。

Guarantee

只有在专门使用适当的 Lonza 推荐的培养基和试剂并遵循推荐的储存和使用协议时，Lonza 才能保证细胞的性能。对推荐的细胞系统进行的任何修改，包括使用替代培养基、试剂或方案，都将使细胞和培养基性能保证失效。如果您在选择合适的培养基、试剂或方案方面需要帮助，请联系 Lonza Scientific Support。

Benefits

HLA information: High-resolution HLA typing (Class I and Class II alleles) is provided

More cells: Increase productivity with larger number of cells available from a single donor

High Purity Viability: Guaranteed to have a purity of ≥90% as indicated by CD34+ expression

High viability: They are guaranteed to contain ≥2 million viable cells per ampoule

Certificate of Analysis is provided for each cell lot purchased. HIV, HBV, HCV not detected

Supporting media: Use X-VIVO^{^®} 20 Medium for the expansion and differentiation

Choices in CD34+ cell types: Cordblood CD34+ HLA typed cells 2C-101 H and 2C-101 HX are available with HLA information. CD34+ cells derived from bone marrow (2M-101) and from adult mobilized blood (4Y-101D) are also available.

Applications

Humanized mice models creation
Regenerative medicine
Autoimmune disease
Transplantations studies
Immunology
Cancer research

Instructions, SDS, CoA

Safety Data Sheets (SDS)

View SDS

SDS – Dutch

SDS – German

SDS – Italian

SDS – Spanish

SDS – French

SDS – English

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

Cord Blood CD34+ ≥2 million cells w/ HLA

Human CD34+ Progenitor Cells from Mobilized Peripheral Blood, Positive Selection, 1 Million 4Y-101C

Human Cord Blood CD34+ Progenitor Cells, Cryopreserved, 500,000 cells 2C-101A

Cord Blood CD34+ ≥2 million cells 2C-101X

Human Cord Blood CD34+ Stem/Progenitor Cells, Cryopreserved, 1 Million cells with HLA 2C-101H

lonza,lonza 2C-101H,人脐带血 CD34+ 干/祖细胞,1 Million cells with HLA

Catalog #: 2C-101H

Cryopreserved ampule of Human Cord Blood CD34+ stem/progenitors containing 1 million cells with HLA information

This product is also available without HLA information if your research does not require it:
≥1 million cells
≥ 2 million cells

Overview

Product Overview

Lonza cord blood CD34+ HLA cells (2C-101H) contain 1 million hematopoietic stem and progenitor cells, and are ideal for studies relating to transplantation and stem cells. They are also widely used in humanized mouse model development. Cord blood derived CD34+ HLA cells (2C-101H) is available with HLA information enabling prescreening and selection of lots most appropriate for your study, providing cost and time savings. HLA information eliminates the need to use cells for obtaining HLA genotype increasing the number of cells that can be used within your experiment. CD34+ HLA cells are ethically sourced and are isolated using Institutional Review Board (IRB) or other regulatory authority-approved consent forms and protocols. Large inventory supports stable supply from a single vendor.

Lonza 脐血 CD34+ HLA 细胞 (2C-101H) 含有 100 万个造血干细胞和祖细胞，是移植和干细胞相关研究的理想选择。它们还广泛用于人源化小鼠模型的开发。脐带血来源的 CD34+ HLA 细胞 (2C-101H) 可提供 HLA 信息，从而能够预筛选和选择最适合您的研究的批次，从而节省成本和时间。 HLA 信息消除了使用细胞获取 HLA 基因型的需要，从而增加了可在您的实验中使用的细胞数量。 CD34+ HLA 细胞的来源符合伦理，并使用机构审查委员会 (IRB) 或其他监管机构批准的同意书和协议进行分离。大库存支持单一供应商的稳定供应。

Guarantee

只有在专门使用适当的 Lonza 推荐的培养基和试剂并遵循推荐的储存和使用协议时，Lonza 才能保证细胞的性能。对推荐的细胞系统进行的任何修改，包括使用替代培养基、试剂或方案，都将使细胞和培养基性能保证失效。

Benefits

HLA information: High-resolution HLA typing (Class I and Class II alleles) is provided

High Purity Viability: Guaranteed to have a purity of ≥90% as indicated by CD34+ expression

High viability: They are guaranteed to contain 1 million viable cells per ampoule

Certificate of Analysis is provided for each cell lot purchased. HIV, HBV, HCV not detected

Supporting media: Use X-VIVO^® 20 Medium for the expansion and differentiation

Choices in CD34+ cell types: Large lots can be selected between (cord blood CD34+ HLA cells 2C-101 HX) and (2C-101 X) (available with and without HLA information). CD34+ cells derived from bone marrow (2M-101) and from adult mobilized blood (4Y-101D) can also be considered

Applications

Humanized mice models creation
Regenerative medicine
Autoimmune disease
Transplantations studies
Immunology
Cancer research

Instructions, SDS, CoA

Safety Data Sheets (SDS)

View SDS

SDS – Dutch

SDS – German

SDS – Italian

SDS – Spanish

SDS – French

SDS – English

Certificate of Analysis (CoA)

Please enter Lot Number, including all zeros, located on the product label and please take into account that it is case sensitive.

Related Products

Human Cord Blood CD34+ Stem/Progenitor Cells, Cryopreserved, 1 Million cells with HLA

Human CD34+ Progenitor Cells from Mobilized Peripheral Blood, Positive Selection, 1 Million 4Y-101C

Human Cord Blood CD34+ Progenitor Cells, Cryopreserved, 500,000 cells 2C-101A

Cord Blood CD34+ ≥2 million cells 2C-101X

Cord Blood CD34+ ≥2 million cells w/ HLA 2C-101HX

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