Di-2-ANEPEQ (JPW 1114)膜电位荧光探针；
Di-2-ANEPE用来测定快速膜电位改变。ANEP染料属于快速反应膜电位染料类。它们的光学反应总够快能检测刺激细胞中瞬时跨膜电位的改变，能证明膜电势依赖激发光谱的转换。
|
规格 |
5 mg |
产品形式 |
粉末 |
|
Ex (nm) |
517 |
Em (nm) |
721 |
|
分子量 |
549.38 |
溶剂 |
Water |
Di-2-ANEPEQ is used for monitoring fast membrane potential changes. ANEP dyes belong to the class of the fast-response membrane potential dyes. Their optical response is fast enough to detect transient membrane potential changes in excitable cells where they demonstrate a membrane potential-dependent shift in excitation spectra. This feature allows the measurement of membrane potential changes by excitation ratio. These dyes are weakly fluorescent in aqueous media, and become strongly fluorescent upon binding to lipophilic environments (such as membranes). In general, fast-response probes operate by means of a change in their electronic structure, and consequently their fluorescence properties, in response to a change in the surrounding electric field. Their optical response is sufficiently fast to detect transient (millisecond) potential changes in excitable cells, including single neurons, cardiac cells and intact brains. However, the magnitude of their potential-dependent fluorescence change is often small; fast-response probes typically show a 2-10% fluorescence change per 100 mV.
储存条件：-20℃
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