lonza,原代细胞和干细胞,NoSpinTM HepaRGTM

Catalog #: NSHPRG

Fully differentiated HepaRGTM cells supplied in a format that does not require centrifugation following thaw. Each ampule contains ≥8.0 million cells.

Product Overview

HepaRGTM Cells are fully-functional, adult-phenotype, human hepatic cells. HepaRGTM Cells exhibit many characteristics similar to primary human hepatocytes and can be used for many of the same applications.  The increased metabolic activity of HepaRG Cells compared to HepG2 enables more predictive value of higher throughput liver toxicity assays conducted in early drug discovery.

The NoSpin HepaRGTM Cells are HepaRG Cells that are provided in a convenient, terminally differentiated, cryopreserved format that does not require the user to centrifuge, resuspend, or count the cells after thawing. This eliminates multiple steps that introduce qualitative and quantitative variability and benefits high-volume labs by reducing the time and effort needed to perform an assay.

Each lot has consistent yield, viability, and functionality across multiple applications.

Using HepaRGTM Cells has never been easier!

Note: The NoSpin HepaRGTM Cells are fully differentiated and non-proliferating.  For the proliferating and non-differentiated version of HepaRGTM Cells, please contact Biopredic International directly.

HepaRGTM 细胞是功能齐全的成人表型人类肝细胞。 HepaRGTM 细胞表现出许多与原代人肝细胞相似的特性,可用于许多相同的应用。与 HepG2 相比,HepaRG 细胞增加的代谢活性使得在早期药物发现中进行的更高通量肝毒性测定具有更高的预测价值。

NoSpin HepaRGTM 细胞是 HepaRG 细胞,以方便的、最终分化的、冷冻保存的形式提供,无需用户在解冻后离心、重悬或计数细胞。这消除了引入定性和定量可变性的多个步骤,并通过减少执行检测所需的时间和精力来使大容量实验室受益。

每个批次在多个应用程序中都具有一致的产量、可行性和功能。

使用 HepaRGTM 细胞从未如此简单!

注意:NoSpin HepaRGTM 细胞是完全分化且不增殖的。对于 HepaRGTM 细胞的增殖和非分化版本,请直接联系 Biopredic International。

Benefits

  • Hepatoctye-like morphology and function
  • Widely accepted as screening tool for liver toxicity
  • No centrifugation step required for higher throughput
  • Greater metabolic activity than HepG2 cells

Applications

  • Drug metabolism
  • infectious disease
  • ADMETox

Content & Storage

Content

1 x Cryopreserved ampule NoSpinTM HepaRGTM containing ≥8 million cells

Data
NoSpinTM HepaRGTM (8.0M cells/vial)

HepaRG CYP Induction chart

Chart displaying cyp induction of HepaRG cells

NoSpinTM HepaRGTM (8.0M cells/vial)

NoSpinTM HepaRGTM (8.0M cells/vial)

The importance of cell-subtype selection in creation of a 3D liver fibrosis model

Data sheet detailing 3D liver fibrosis model in collaboration with Viskol

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