lonza CC-2586,CC-2511,原代细胞和干细胞,NHEM-Ad-成人表皮黑色素细胞

Catalog #: CC-2586
NHEM-Ad, Epidermal Melanocytes, Adult
Overview

Product Overview

成人和新生儿人类表皮黑色素细胞 (NHEM) 是位于所有哺乳动物皮肤表皮层的色素生成细胞。黑色素细胞的功能是产生黑色素,黑色素是赋予皮肤颜色的色素。黑色素保护皮肤免受紫外线伤害。皮肤由2个主要层组成,表皮和真皮。表皮由多个角质形成细胞层组成。黑素细胞位于表皮的基底层。星状或树突状黑素细胞形态允许黑素细胞细胞体驻留在表皮的基底层,而树突与表皮上层的角质形成细胞结合。这种关联允许黑色素细胞将黑色素从细胞体通过树突转运到角质形成细胞中,从而导致皮肤着色。

黑素细胞研究有两个主要领域——化妆品和医学。化妆品研究中心专注于改变皮肤颜色的能力。医学研究通常集中在黑色素瘤以及各种皮肤病或相关疾病,如白化病和白癜风、激素治疗、甲状腺疾病、牛皮癣、烧伤和疤痕。

Our Cryopreserved Normal Human Epidermal Melanocytes are guaranteed through 8 population doublings, express Mel-5 and L-Dopa conversion to melanin.  All cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Note: Melanocytes are extremely sensitive to over trypsinization. Use Lonza’s Trypsin/EDTA Solution (CC-5012) and dilute 1:1 with Versene®(17-711E) prior to use.

 

Content & Storage

Content

1 x Cryopreserved Ampule with ≥500,000 cells/vial

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