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Product Overview

Bone marrow mononuclear cells (common abbreviations: BMNC, BM MNC, and BM-MNC) are a mixed population of single nucleus cells including monocytes, lymphocytes, and hematopoietic stem and progenitor cells.

骨髓单个核细胞（常用缩写：BMNC、BM MNC 和 BM-MNC）是单核细胞的混合群体，包括单核细胞、淋巴细胞以及造血干细胞和祖细胞。

BMNCs You Can Count on to Perform

Cryopreserved Lonza Bone Marrow Mononuclear Cells are isolated from whole bone marrow via density gradient separation. Isolating mononuclear cells eliminates erythrocytes and graulocytes, producing a more stable cell product. Lonza BMNCs are available fresh or frozen from a large and varied donor pool. They are guaranteed to contain either ≥5, 25, 100, 200 and 300 million viable cells per ampoule, depending upon product purchased. Fresh cells are suspended in HBSS with 5 mM EDTA and 0.5% BSA and are available in a variety of cells per vial packaging sizes. Fresh BMNC orders require a minimum order quantity of two vials per donor. Please contact Customer Service for information on sizes and pricing for fresh cells.

通过密度梯度分离从全骨髓中分离冷冻保存的龙沙骨髓单核细胞。 分离单核细胞消除红细胞和粒细胞，产生更稳定的细胞产物。 Lonza BMNCs 可从大量多样的供体库中获得新鲜或冷冻。 根据购买的产品，它们保证每个安瓿含有≥5、25、100、200 和 3 亿个活细胞。 新鲜细胞悬浮在含有 5 mM EDTA 和 0.5% BSA 的 HBSS 中，每瓶包装尺寸有多种细胞可供选择。 新鲜的 BMNC 订单要求每个捐赠者至少订购两瓶。 有关新鲜细胞的尺寸和价格信息，请联系客户服务。

Choices in Cell Type and Tissue Source

Lonza offers choices in cell type and tissue source so you can choose the right product for your research and budget needs. Depending upon your ultimate cell of choice, you can choose from unprocessed bone marrow, bone marrow MNCs, bone marrow CD34+ cells, bone marrow stromal cells (for use as feeder cells), or bone marrow mesenchymal stem cells. In addition, if bone marrow is not your preferred tissue source, we also offer cord blood derived cells.

Lonza 提供细胞类型和组织来源的选择，因此您可以选择适合您的研究和预算需求的产品。 根据您选择的最终细胞，您可以选择未加工的骨髓、骨髓 MNC、骨髓 CD34+ 细胞、骨髓基质细胞（用作饲养细胞）或骨髓间充质干细胞。 此外，如果骨髓不是您首选的组织来源，我们还提供脐带血来源的细胞。

Supported by an Optimized Culture System

HPGM^TM Hematopoietic Growth Medium is recommended for optimal performance in serum-free culturing (additional cytokines may be necessary depending on application). Alternative media containing serum may also be acceptable. Please contact Scientific Support for serum containing media recommendations.

Lonza guarantees the performance of Clonetics^TM/Poietics^TM cells only if appropriate Clonetics^TM/Poietics^TM media and reagents are used exclusively and the recommended storage and use protocols are followed. Any modifications made to the recommended cell systems including the use of alternative media, reagents or protocols, will void cell and media performance guarantees. If you need assistance in selecting the appropriate media, reagents, or protocol, please contact Lonza Scientific Support.

建议使用 HPGMTM 造血生长培养基以在无血清培养中获得最佳性能（根据应用，可能需要额外的细胞因子）。 含有血清的替代培养基也是可以接受的。 有关含血清培养基的建议，请联系科学支持。

只有在专门使用适当的 CloneticsTM/PoieticsTM 培养基和试剂并遵循推荐的储存和使用协议时，Lonza 才能保证 CloneticsTM/PoieticsTM 细胞的性能。 对推荐的细胞系统进行的任何修改，包括使用替代培养基、试剂或方案，都将使细胞和培养基性能保证失效。 如果您在选择合适的培养基、试剂或方案方面需要帮助，请联系 Lonza Scientific Support。

Safety Data Sheets (SDS)