lonza00195275S,D-HBE-COPD,患病的人支气管/气管上皮细胞,B-ALITM 的慢性阻塞性肺病

Product Overview

Chronic bronchitis is marked by long-term cough and excess mucous. Emphysema leads to the destruction of the lungs over time. Most people with COPD have a combination of both conditions. Usually COPD is associated with bronchial epithelium changes.

Cryopreserved diseased human bronchial epithelial cells from donors diagnosed with COPD are screened for air liquid interface differentiation. These cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased.

Our catalog number 00195275S are suitable for air-liquid interface studies and are guaranteed to promote full differentiation of the airway epithelium expressed by the formation of a polarized epithelium with good barrier function (transepithelial resistance), secretory phenotype (mucin secretion) and ciliogenesis. Differentiation usually will occur by day 22 in culture.

慢性支气管炎的特点是长期咳嗽和粘液过多。 随着时间的推移，肺气肿会导致肺部受损。 大多数患有慢性阻塞性肺病的人同时存在这两种情况。 通常COPD与支气管上皮变化有关。

对来自诊断为 COPD 的供体的冷冻保存的患病人支气管上皮细胞进行气液界面分化筛选。 这些细胞的支原体、细菌、酵母和真菌检测呈阴性。 并非所有供体和/或细胞批次都检测到 HIV-1、乙型肝炎和丙型肝炎。 为购买的每个细胞批次提供分析证书。

我们的目录号 00195275S 适用于气液界面研究，并保证促进气道上皮的完全分化，通过形成具有良好屏障功能（跨上皮阻力）、分泌表型（粘蛋白分泌）和纤毛发生的极化上皮表达。 分化通常会在培养的第 22 天发生。