Acepromazine maleate;乙酰丙嗪马来酸酯;
分子式:C19H22N2OS · C4H4O4 分子量 442.53
溶解性:water 10mg/Ml
储存条件:零下20摄氏度
Application
Acepromazine is a phenothiazine and an analogue of the antipsychotic drug chlorpromazine. Acepromazine is thought to block dopamine receptors in the brain, and inhibit ABCG2 transport protein whose overexpression in tumors is associated with drug resistance.
Biochem/physiol Actions
Acepromazine is a phenothiazine antipsychotic comonly used as a veterinary drug (horses, dogs and cats). The compound is an analogue antipsychotic drug chlorpromazine. The drug is thought to block receptors of dopamine in the brain. Recently it was discover that the compound inhibits ABCG2 transported protein, which overexpression in tumors is associated with drug resistance.
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